Journal article
MMRdb: Measles, mumps, and rubella viruses database and analysis resource


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Publication Details
Author list: Iman Almansour and Mazen Alhagri
Publisher: Elsevier
Publication year: 2019
Journal: Infection, Genetics and Evolution
Journal name in source: Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases
Volume number: 75
Issue number: November 2019
Start page: 1
End page: 6
Number of pages: 6
ISSN: 1567-1348
Web of Science ID:
PubMed ID: 31352145
Scopus ID: 85070696370
eISSN: 1567-7257


Measles, mumps, and rubella viruses are well known human pathogens that cause mild to severe illnesses. Despite the existence of MMR vaccines since 1971, outbreaks have been largely documented even in highly vaccinated populations. There is a pressing need to develop a resource to monitor genetic and antigenic variations among these viruses. Here, we introduced MMRdb, a web central database and analysis resource for measles, mumps, and rubella viruses. Users can search viruses at gene level and obtain sequence information based on gene product, geographic location, year, or host. The MMRdb also catalogs experimentally verified B cells and T cells antigenic epitopes data. A set of computation tools such as multiple sequence alignment, Geo Chart, and sequence similarity BLAST search has been implemented in a user-friendly database. The main features of this database will assist researchers in monitoring genetics and antigenic variations, tracking geographic spread with regards of sequence information, and facilitate the development of diagnostics, vaccines, and immunotherapeutics. Database URL: http://mmrdb.org.

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Last updated on 2019-11-09 at 09:13